Theodore J. Kaczynski, the so-called Unabomber, died on Saturday in a federal prison medical center in Butner, N.C. He was 81.
Kaczynski attacked academics, businessmen and random civilians with homemade bombs from 1978 to 1995, becoming one of the most feared sociopaths of his day.
His bombs killed three people and injured 23, his stated goal being the collapse of the modern social order — a violent spree that ended after what was often described as the longest and most costly manhunt in American history.
A spokesman for the Federal Bureau of Prisons said Mr. Kaczynski was found unresponsive in his cell early in the morning. The cause of death was not immediately known.

Mr. Kaczynski’s life was singularly interesting, a case study in the making of a sociopath: lonely boy genius who was always a misfit, Harvard-trained star of pure mathematics, rural recluse, and notorious murderer, and finally, imprisoned extremist. After his arrest in April 1996, extraordinary details emerged. He had scored 167 on an I.Q. test as a boy and entered Harvard at 16. In graduate school, at the University of Michigan, he worked in a field of mathematics so esoteric that a member of his dissertation committee estimated that only 10 or 12 people in the country understood it. By 25, he was an associate professor at the University of California, Berkeley.
In the public eye, he fused a rare mix of styles of violence: the periodic targeting of the demented serial killer and the ideological fanaticism of the terrorist.
After he was captured by about 40 F.B.I. agents, the details of that ideology were expounded in a 35,000-word manifesto that Mr. Kaczynski wrote to justify his actions and evangelize the ideas that he claimed inspired them.
Psychologists involved in the trial saw his writing as evidence of schizophrenia. His lawyers tried to mount an insanity defense — and when Mr. Kaczynski rebelled and sought to represent himself in court, risking execution to do so, his lawyers said that was yet further evidence of insanity.
He acquired the reputation of a twisted reveler in violence, picking victims seemingly at random, known only by a mysterious-sounding nickname with roots in the F.B.I.’s investigation into him: “the Unabomber.” It became widely publicized that some of his victims lost their fingers while opening a package bomb. Going through the mail, among the unconscious routines of daily life, prompted flickers of nervousness in many Americans.
Starting in 1971 and continuing until his arrest, he lived in a shack he built himself in rural Montana. He forsook running water, read by the light of homemade candles, stopped filing federal tax returns and subsisted on rabbits.
Kaczynski was serving out eight consecutive life sentences without the possibility of parole.